Effects of Chaga Extract.

Chaga is Inonotus obliquus, and its sclerotium is tumor-like (sterile mass). It is mainly distributed in Russia, Finland and other regions in the northern hemisphere at 40° to 50° north latitude, and in Heilongjiang and Jilin in China. Inonotus obliquus (Chaga extract) is a folk medicinal fungus in Russia, and its active ingredients have attracted widespread attention from researchers in the United States, Japan and other countries. According to preliminary research, Inonotus obliquus contains inonotus alcohol, oxidized triterpenoids, lanosterol, traemonic acid, folic acid derivatives, aromatic vanillic acid, syringic acid, etc., which have anti-cancer, blood pressure lowering, blood sugar lowering, and immune revitalizing effects.

In 1955, the Medical Academy of Science in Moscow announced that Inonotus obliquus was an anti-cancer substance; the United States listed Inonotus obliquus as a "special natural substance" as a future drink for spacemen; Japan used Inonotus obliquus as a treatment for liver cancer, AIDS and 0-157 E. coli poisoning, and applied for a number of patents related to Inonotus obliquus. The United States, Japan, and South Korea have increased their research efforts on Inonotus obliquus.

1) Folic acid derivatives (Pteroiploglutamic), and aromatic substances: Aromaticvanillicacis, Syringicacid and -hydroxybenzoicacid.

2) Inooidiol (エルゴステロ一ル, with a high content of 35.5mg/100g) and fuscoporine.

3) Various oxygenated triterpenes, such as 3β-hydroxy-8, 24-dienlanosta-21, 23-1actone, 21, 24-cyclopentalanosta-3β, 21, 25-triol-8-ene, 3β, 22, 25-trihy-droxy-lanosta-8-ene: Various lanosterol triterpenes, such as 3β-hydroxylanosta-8, 24-diene-21-a1, 3β, 21-dihydroxy-lanosta-8, 24-diene, 3β-hydroxy-lanosta-8, 24-diene-21-acid, 3β, 22R-dihydroxy-lanosta-8, 24-diene, ergosterolperoxide, phinginod analogs and mannitol.

4) Steroids, alkaloid-oramin-like compounds and Trametenoic acid.

After the research of countries around the world in recent years and long-term animal experiments and clinical experiments, it is shown that the use of Chaga has no toxic side effects, and the medicinal effects are as follows:

1) Treatment of diabetes

Using Chaga ultrafine powder to treat diabetic patients, the results show that after treatment, the whole blood viscosity and plasma viscosity of patients are lower than before treatment, and fibrinogen, hematocrit, and red blood cell aggregation index are significantly lower than before treatment. The cure rate of birch mushroom powder of Komsomlshi Pharmaceutical Company in Russia for diabetes is 93%.

2) Anti-cancer effect

It has a significant inhibitory effect on a variety of tumor cells (such as breast cancer, lip cancer, gastric cancer, parotid gland cancer, lung cancer, skin cancer, rectal cancer, Hawkins lymphoma). Prevent cancer cell metastasis and recurrence, and enhance immunity. It is also used to cooperate with radiotherapy and chemotherapy for patients with malignant tumors to enhance the patient's tolerance and reduce toxic side effects.

3) Prevention and treatment of AIDS

It has a significant inhibitory effect on AIDS. El-Mekkawy et al. (1998) reported that the triterpenoid compounds ganoderiolF and ganodermanontriol can significantly inhibit the cytopathic effect of HIV-ld on MT-4 cells; the fruiting bodies of Chaga and the active ingredients contained in Chaga, especially the triterpenoid compounds, can inhibit the proliferation of HIV in vitro; the anti-HIV effect of Chaga may be related to its inhibition of HIV reverse transcriptase and protease activity. This effect needs to be further confirmed by in vivo administration.

4) Anti-aging, inhibition of infectious viruses and prevention of colds

Immune function decline is one of the most obvious characteristics of aging. Among the immune organs, the function of B cells regulated by the thymus and bone marrow and their ability to secrete immunoglobulins decline. These changes lead to a weakening of the immune function of middle-aged and elderly people against external antigens and a decrease in the ability to monitor mutated antigens. Modern research has shown that the decline in immune function caused by aging can be delayed and partially restored. Among the many measures and drugs for preventing and treating immune function decline, Chinese medicine for strengthening and replenishing the body has been proven to be effective. Chaga can remove free radicals in the body, protect cells, prolong the number of cell divisions, increase cell lifespan, and promote metabolism, thus effectively delaying aging. Long-term use can prolong life.

5) Preventing hypertension

Experimental studies have shown that Chaga can lower the blood pressure of patients with hypertension and relieve symptoms. In particular, it has a coordinated effect when used in combination with conventional antihypertensive drugs, making blood pressure easier to control and more stable. In addition, it can also improve the subjective symptoms of patients with hypertension. It is reported that Chaga is not only a tonic, but also a blood cleanser and pain reliever.

6) Improve and prevent allergic constitution, and has a significant therapeutic effect on hepatitis, gastritis, duodenal ulcers, nephritis, and has a therapeutic effect on vomiting, diarrhea, and gastrointestinal dysfunction.

A method for preparing a Chaga extract, comprising the following steps:

(1) coarsely crushing Chaga (raw material 1-from Siberia) to a particle size of about 1 mm to obtain Chaga powder;

(2) placing 10 g of Chaga powder in a container and injecting a soaking liquid; the soaking liquid is prepared with distilled water as a solvent, containing 10% dimethyl sulfoxide and 6% sodium hydroxide (i.e., 2.55% hydroxide ions) by mass, and the amount of the soaking liquid is 4 times the weight of the Chaga powder, so that the soaking liquid Completely soak the powder; let the mixture stand at room temperature for 1.5 hours;

(3) Filter the mixture after standing, take the filter residue, and discard the filtrate;

(4) Inject 60mL of distilled water into the filter residue, heat to 70℃, and keep for 5 hours; filter to obtain the secondary filtrate;

(5) Inject 40mL of distilled water into the filter residue obtained by filtration in step (4), heat to 70℃, and keep for 5 hours; filter to obtain the second filtrate;

(6) Mix the two filtrates and dry them to obtain a solid extract.