WS-23 Cooling Agent: The Ultimate Flavor-Neutral Cooling Sensation for Modern Industries

Jun 12, 2026

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Introduction: What Is WS-23 Cooling Agent?


WS-23 cooling agent (chemical name: N,2,3-Trimethyl-2-isopropylbutamide, CAS No. 51115-67-4, FEMA 3804) is a premium synthetic cooling agent delivering a clean, fast, flavorless cooling sensation without menthol's strong minty taste or throat irritation. As a leading non-menthol cooling agent, it activates TRPM8 cold receptors for instant refreshment-4–10× more potent than natural menthol, with zero aftertaste and high heat stability (up to 200°C).


Widely known as Koolada WS-23, it's the gold standard for modern formulations where flavor fidelity and smooth cooling matter most.

 

WS-23 Cooling Agent


Key Benefits of WS-23 Cooling Agent


Why choose WS-23 powder over menthol or other synthetic coolants (WS-3, WS-5, Frescolat ML)?


✅ Flavor-Neutral Cooling: No minty, bitter, or medicinal notes-preserves original flavors (fruit, dessert, herbal).


✅ Fast Onset, Clean Finish: Cooling hits instantly (tongue/front mouth), fades smoothly without lingering harshness.


✅ Zero Throat Hit: Non-irritating, ideal for high-nicotine vapes and sensitive oral care.


✅ High Purity & Stability: ≥99% white crystalline powder; heat-resistant, pH-stable, 3-year shelf life.


✅ Cost-Effective: Lower usage rates (0.2–3.0%) vs. menthol; less sensory fatigue.


✅ Regulatory Approved: FDA (GRAS), EFSA, FEMA 3804-safe for food, cosmetics, pharmaceuticals.


Top Applications of WS-23 Cooling Agent


1. Vaping & E-Liquids (Fastest-Growing Segment)


WS-23 for vape juice dominates "ice" flavors (mango ice, watermelon ice) and nicotine salt disposables (20–50mg/mL). It smooths harsh nicotine, boosts refreshment, and won't mask fruit profiles-the most popular cooling agent in vaping.


Usage: 0.5–1.5% in e-liquids; 1.0–3.0% for "super ice" disposables.


2. Food & Beverages


WS-23 cooling agent for food enhances refreshment without altering taste:


Confectionery: Mints, chewing gum, hard candies (offsets sweetener warmth).


Beverages: Carbonated drinks, energy drinks, iced teas, flavored waters.


Dairy: Ice cream, yogurt, sorbets (amplifies cold perception).


3. Cosmetics & Personal Care


WS-23 for cosmetics delivers soothing, non-irritating cooling:


Skincare: After-sun gels (0.8–1.2%), toners (0.3–0.6%), cooling masks.


Oral Care: Toothpaste (0.8–1.2%), mouthwash (1.0–1.5%)-mint-free freshness.


Hair Care: Anti-dandruff shampoos, scalp treatments (relieves itchiness).


Shaving: Gels, aftershaves (reduces irritation, cooling comfort).


4. Pharmaceuticals


WS-23 in pharmaceuticals improves palatability and soothing:


Oral meds: Mask bitter tastes in syrups, tablets, lozenges.


Topicals: Analgesics, muscle rubs, burn gels (cooling relief).


WS-23 vs. Other Cooling Agents: A Quick Comparison

 

Cooling AgentCooling IntensityFlavorThroat IrritationBest For

WS-23

High (100)None❌ ZeroVapes, fruit flavors, oral care
MentholMediumStrong Mint✅ CommonTraditional mints, low-intensity cooling
WS-3Medium-HighNone✅ MildThroat cooling, e-liquids
WS-5Very HighNone✅ ModerateExtreme cooling, "super ice"

 

WS-23 stands out for its balanced intensity, flavor neutrality, and zero irritation-ideal for mainstream consumer products.

 

WS-23

 

Global Market Trends for WS-23 Cooling Agent (2025–2030)


The WS-23 cooling agent market is expanding rapidly, driven by demand for sensory innovation and clean-label ingredients:


Vaping Boom: The largest end-use sector-demand surges for fruit-ice vapes and smooth nicotine salts.


Clean Label Shift: Brands prefer synthetic cooling agents like WS-23 over menthol for consistency and no allergens.


APAC Growth: China, South Korea, and Southeast Asia lead consumption in cosmetics, food, and vaping.


Premiumization: High-purity (≥99%) WS-23 powder commands premium pricing in B2B supply chains.


Regulatory Tailwinds: Global safety approvals (FDA, EFSA) fuel adoption in pharmaceuticals and oral care.


Market analysts project a CAGR of 7.2% for WS-23 through 2030, with the vaping segment accounting for over 50% of total demand.


Why Buy High-Purity WS-23 Cooling Agent From Us?


Looking for a reliable WS-23 supplier? We offer:


✅ 99%+ Pure WS-23 Powder: CAS 51115-67-4, FEMA 3804, ISO/SGS/GMP certified.


✅ Bulk & Wholesale Pricing: MOQ 100g; flexible OEM packaging.


✅ Fast Global Shipping: Secure delivery to US, EU, UK, APAC.


✅ Technical Support: Formulation guidance for vapes, food, cosmetics.


👉 Shop WS-23 Cooling Agent Now


Final Thoughts


WS-23 cooling agent is more than a sensory additive-it's a formulation game-changer. With its clean cooling, flavor neutrality, and versatile applications, it's the top choice for modern brands in vaping, food, cosmetics, and pharmaceuticals.


As the demand for non-menthol cooling agents rises, high-quality WS-23 powder will remain essential for creating standout products that consumers love.